Conveniently located off Interstate 81 and U.S. Route 460, the smoke-free Comfort Inn hotel in Blacksburg, VA is located just minutes from Virginia Polytechnic Institute and State University (Virginia Tech). Our hotel is also just a short drive from Roanoke Regional Airport, Radford University, Lane Stadium, Virginia Tech Corporate Research Center, Edward Via College of Osteopathic Medicine, Lewis Gale Montgomery Hospital and Warm Heart Village. At our pet-friendly hotel, guests can enjoy amenities like a free hot breakfast, free Wi-Fi, free local shuttle (please call the hotel for details), a seasonal outdoor pool, fitness center and business center. Our inviting guest rooms feature flat-screen TVs, hair dryers, coffee makers, microwaves, refrigerators and more. We look forward to your stay at the Comfort Inn hotel in Blacksburg, VA. Book today!