The Walterboro, SC Comfort Inn & Suites hotel is off Interstate 95, less than five miles from the University of South Carolina Salkehatchie and the Colleton Museum of history. We are minutes from Edisto Beach, Colleton State Park, South Carolina Artisans Center, Colleton County Memorial Library, Bonnie Doone Plantation and numerous restaurants. Free amenities include high-speed Internet access, newspaper, local calls, seasonal outdoor pool and fitness center. We offer free hot breakfast. Business travelers will appreciate free coffee, our business center and that we offer copy and fax services. Rooms have refrigerators, microwaves, irons and boards, coffee makers and hairdryers. We have a whirlpool room with a king bed. Smoke-free hotel. From the moment you walk through the doors at the Comfort Inn & Suites hotel, you'll experience Southern hospitality at its best. Book your room today.