The Comfort Inn & Suites at I-85 hotel in Spartanburg, SC is minutes from downtown Spartanburg and Spartanburg Regional Hospital. Also nearby our pet-friendly hotel are Mary Black Memorial Hospital, Sherman College of Chiropractic, University of South Carolina Upstate, Converse College and Wofford College. Be sure to check out Hatcher Garden & Woodland Preserve, Cowpens National Battlefield, Chapman Cultural Center, Hollywild Animal Park and BMW Zentrum- Manufacturing Plant. The Gaffney Premium Outlets are just a short drive away. Free amenities include Wi-Fi, fitness center and outdoor pool. We offer free hot breakfast with delicious options like waffles. Business travelers can access our business center, copy and fax services. Host your next event in our meeting room! Rooms have desks, coffee makers, microwaves, refrigerators and TVs. Ask about our whirlpool suites! Our smoke-free hotel also offers guest laundry facilities. Book today at the Comfort Inn & Suites at I-85 in Spartanburg, SC!