Book today at the Comfort Suites Greenville South hotel in Piedmont, SC! Our smoke-free hotel is located off I-85 and gives you easy access to businesses and attractions in Greenville, Anderson and Easley. When you're in the area, check out the Falls Park on the Reedy, Greenville Zoo and the Peace Center of the Performing Arts. Coming for an event? We are conveniently located near Bon Secours Wellness Arena and the TD Convention Center. Also nearby are companies like Michelin and Lockheed as well as institutions like Clemson University and Shriner's Hospital. Amenities include free hot breakfast, free WiFi, fitness center, indoor heated saline pool and more. Ask about our meeting packages! Rooms feature a microwave, refrigerator, flat screen TV and sofa sleeper. Book your room today at the Comfort Suites Greenville South hotel in Piedmont, SC!