Book your stay at the Comfort Inn hotel in Antioch, CA! Our affordable hotel is conveniently located off Highway 4. Experience some of the best attractions Antioch has to offer near our hotel including Black Diamond Mines Regional Preserve, Concord Pavilion, Century Plaza Shopping Center, and Contra Costa County Event Center. Get the best value when you visit your loved one at nearby Los Medanos College when you stay at our hotel in Antioch, CA. Amenities include free hot breakfast with waffles, free WiFi, an outdoor pool, fitness center, and a business center. All guest rooms include a microwave and refrigerator, coffee maker and flat-panel TV. Book now!